• CLL associated HLH was first documented in

  2019-05-23

  

  CLL associated HLH was first documented in the form of a case series report which included six patients treated for CLL who subsequently developed the phagocytic syndrome months to years later.[7] As these cases occurred prior to publication of the 1991 HLH diagnostic guidelines, the authors postula

• Findings Three factors were significant predictors

  2019-05-23

  

  Findings Three factors were significant predictors of treatment failure: the presence of at least 1 month of fair or poor adherence (OR 15·7, 95% CI 1·8–136·7; p=0·01); previous treatment at another clinic before the WWO/AHF Family Health Clinic (1·4, 1·2–13·7; p=0·02); and tuberculosis symptoms at

• br Mega cohort studies Remote monitoring collects a

  2019-05-23

  

  Mega-cohort studies Remote monitoring collects a wealth of data from large numbers of patients which are not subject to saturation or overwritten memory counters within any implantable device. These databases provide an opportunity to better understand system function, patient condition, and dise

• The GCT usually involves a cladding

  2019-05-23

  

  The GCT usually involves a cladding that consisted of reactive bone and fibrosis, with a distinct boundary surrounded by soft tissue. Nevertheless, the active cladding is very thin among patients with severe invasiveness, including tumors that extend directly in into the muscle and fat, or other sig

• Your support for the official

  2019-05-23

  

  Your support for the , official journal of the Japan Heart Rhythm Society (JHRS) and the Asia Pacific Heart Rhythm Society (APHRS), is sincerely appreciated. We are pleased to announce that JOA has become an open access journal. Thus it is always available for readers online. All articles are acces

• Introduction Atrial fibrillation AF is the

  2019-05-23

  

  Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia managed in clinical practice and the most common arrhythmia requiring hospitalization [1,2]. Thromboembolism occurs with similar incidence, regardless of the form of AF [3,4]. AF management includes anticoagulation to prev

• Prior case reports have described hematological remission in

  2019-05-23

  

  Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic vorinostat on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we re

• There is also a pressing need to change the

  2019-05-23

  

  There is also a pressing need to change the way societal and mitotic inhibitor progress is measured to more accurately reflect an ecosocial approach to health. We are thus interested in applying the Happy Planet Index (HPI) at a community as well as at a national level. The HPI, an innovative measu

• BMN673 Air pollution also has a

  2019-05-23

  

  Air pollution also has a substantial effect on the wellbeing of people worldwide. This pollution can consist of sulfur dioxide, ozone, nitrogen dioxide, and fine-particulate BMN673 of less than 2·5 μm in diameter (PM). 92% of the global population is exposed to higher-than-recommended concentrations

• Assim como forma de ep logo que ligue

  2019-05-22

  

  Assim, como forma de epílogo que ligue essa ideia central defendida por nós, citamos o editorial de lançamento da revista Araucaria de Chile, que, em 1978, afirmava: Bien se sabe que Chile no es una isla ni su tragedia combate un accidente ni un caso de excepción en América Latina. Su situación se

• Los dedos son las cuatro mil verdades

  2019-05-22

  

  Los dedos son las cuatro mil verdades vistas por los ojos de las moscas. La labor del escritor, entonces, se pone Immunology Inflammation Compound Library la altura de la labor del detective: encontrar los diez dedos, descubrir el cuerpo flotando en el agua, dar con una cabeza que yace en el fondo d

• br Identidade negra e quilombola O uso da

  2019-05-22

  

  Identidade negra e quilombola O uso da expressão “remanescentes” para classificar os agrupamentos negros, enquanto unidades que guardam correspondência histórica com os quilombos, motivou reflexões sobre seu significado. Adotamos o entendimento de que ao contrário do sentido de sobra ao qual pode

• br Authorship br Conflict of interest

  2019-05-22

  

  Authorship Conflict of interest Acknowledgments The Leukemia & Lymphoma Society supported CRC with a Scholar in Clinical Research award (2400-13). This work was supported by the Gatorade Trust from the University of Florida Department of Medicine. Introduction Klinefelter syndrome (KS),

• br AML therapies with curative intent br

  2019-05-22

  

  AML therapies with curative intent Alternative treatment strategies Targeted therapies: the new kids on the block The recognition of specific mutations as genetic drivers or facilitators of AML has led to the development of new inhibitors and targeted treatment options. New promising drug c

• Introduction Acute myeloid leukemia AML is a rare disease

  2019-05-22

  

  Introduction Acute myeloid leukemia (AML) is a rare disease afflicting annually 3–4 persons per 100,000 individuals. With a median age at diagnosis of 67 years, this disease is far more common in the elderly [1]. In this age group, AML has a particularly dismal outcome with less than 5% of the pati

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